A response to the open peer commentaries on "Young people's experiences of participation in clinical trials: Reasons for taking part".

In our target article “Young People’s Experiences of Participation in Clinical Trials: Reasons for Taking Part” (Luchtenberg et al. 2015), we stated that young people’s 15 reasons for taking part included both personal benefit and helping others. Regarding personal benefit, young people’s experiences covered a wide range of interwoven motivations, which include much more than just health benefit. Participation also contributed to enrich-20 ment of their personal life and dealing with their disease. The young people felt special and acquired more confidence. Our participants wanted to help future patients, parents, and their doctors. In addition, they experienced a feeling of moral duty and acknowledged 25 the contribution made by past generations. For helping others in general, we introduced the term “network of exchange.” When participants specifically aimed at helping future patients to acknowledge contribution made by patients in the past, we referred to 30 “intergenerational solidarity.” We argued that professionals should not be reluctant to ask young people to participate in clinical trials; they should be more open about research opportunities, and should provide better information